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Out Of Mind » THE INSANITY OF REALITY » SCIENCE » The astonishing village where little girls turn into boys aged 12 in the Dominican Republic

The astonishing village where little girls turn into boys aged 12 in the Dominican Republic

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[size=37]The astonishing village where little girls turn into boys aged 12  [/size]
In a remote village in the Dominican Republic girls become boys at puberty because of a rare genetic disorder


Catherine and his cousin Carla photo credit BBC/Jon Sayers




In every way, Johnny is physically and biologically male. But, astonishingly he did not grow a penis until he hit puberty.

He is one of many children who live in Salinas, an isolated village in the southwestern Dominican Republic, who are seemingly born female, only to become men in their teenage years.

Although Johnny’s story may seem extraordinary, cases of little girls turning into boys are so prevalent in the village that it is no longer considered abnormal. The children are simply referred to as the ‘guevedoces’ – which literally translates as ‘penis at 12’

Johnny, 24, was originally named Felecitia by his parents and brought up as a girl. He spoke to Dr Michael Mosley for the new BBC2 series “Countdown to Life – the extraordinary making of you"

 “I remember I used to wear a little red dress,” he said. “I was born at home instead of in a hospital. They didn’t know what sex I was.

“I went to school and I used to wear my skirt. I never liked to dress as a girl. When they bought me girls toys I never bothered playing with them. All I wanted to do was play with the boys.”


 

Johnny, who was seemingly born as a girl but turned into a boy aged seven


The rare genetic disorder occurs because of a missing enzyme which prevents the production of a specific form of the male sex hormone - dihydro-testosterone - in the womb.

All babies in the womb, whether male or female, have internal glands known as gonads and a small bump between their legs called a tubercle. At around eight weeks, male babies who carry the Y chromosome start to produce dihydro-testosterone in large amounts, which turns the tubercle into a penis. For females, the tubercle becomes a clitoris.

But some male babies are missing the enzyme 5-α-reductase which triggers the hormone surge, so they appear to be born female with no testes and what appears to be a vagina. It is not until puberty, when another huge surge of testosterone is produced, that the male reproductive organs emerge. What should have happened in the womb happens around 12 years later. Their voices deepen and they finally grow a penis.

For Johnny it happened at the age of seven. He claimed that he had never felt like a little girl and was far happier after he fully became a boy.

“When I changed I was happy with my life,” he said.

A little girl named Carla is currently going through the same transformation, aged nine. Despite being brought up as a girl, his mother noticed that from the age of five he was more inclined towards the rough and tumble play of little boys. He has recently had his hair cut shirt after wearing plaits for years.

“I feel like a man now,” he said.

Many decide not to change from their female names, so some men in Salinas have names like Catherine.

The guevedoces were first discovered by a Cornell University endocrinologist Dr Julianne Imperato in the 1970s who travelled to Dominican Republic after hearing strange rumours about girls turning into boys.

Further cases have since been seen in the Sambian villages of Papua New Guinea although the Sambians view the children as flawed males and they are often shunned, unlike the Dominicans who welcome the transformation with widespread celebration.


 
Dr Michael Mosely


Dr Mosley said: “I hated going through puberty; voice cracking, swinging moods, older brother laughing at me. But compared to Johnny, I had it easy.

“Guevedoces are also sometimes called “machihembras” meaning “first a woman, then a man”. When they’re born they look like girls with no testes and what appears to be a vagina. It is only when they near puberty that the penis grows and testicles descend.

“When Dr Imperato investigated the Guavadoces she discovered the reason they don’t have male genitalia at birth is because they are deficient in an enzyme called 5-α-reductase, which normally converts testosterone into dihydro-testosterone.

“By a quirk of chance Dr Imperato’s research was picked up by the American pharmaceutical giant, Merck. They used her discovery to create a drug called finasteride, which blocks the action of 5-α-reductase.

“It is now widely used to treat benign enlargement of the prostate and male pattern baldness. For which, I’m sure, many men are truly grateful.”

Around one in 90 children in Salinas are guevedoces and although they resemble sexually normal males, subtle differences do still exist in adulthood. Most have decreased amounts of facial hair and smaller prostate glands relative to the average male.

It is thought that the condition has persisted through generations because of the isolation of the villagers. Because the disorder is so widespread and accepted, the Dominican Republic now believes that there are three sexual categories, male, female, and pseudohermaphrodite.


Growing a penis at 12: the 'Guevedoce' boys of the Dominican Republic
 
By Dr Michael Mosely


…We came across Johnny when we were filming for a new BBC2 series, “Countdown to Life”, which looks at the consequences of normal, and abnormal, developments in the womb.

Johnny is known as a “Guevedoce”, which literally means, “penis at twelve”. And the reason he’s called that is because, like 1 in 90 of the boys in the area, he first started to grow a penis when he was going through puberty…

Johnny, who is now in his 20s, was once known as Felicita. He was brought up as a girl and remembers going to school in a little red dress.

When he was young he would happily play with other little girls, but after the age of seven he started to change

“I did not feel good, I no longer liked to wear a skirt, and I was no longer drawn to play with girls. All I wanted to do is play with toy guns and boys”

When he turned obviously male he was teased at school because”, as he put it, “it is hard to imagine a girl that is now is a boy”.

One of the first people to study this unusual condition was Dr Julianne Imperato, a Cornell endocrinologist. She travelled to this remote part of the Dominican Republic in the 1970s because of strange rumours about girls turning into boys

She eventually unraveled the mystery of what is going on and by doing so helped make a surprising medical breakthrough.

At conception we all inherit a set of genes from our parents that will, in time instruct our bodies to make us male or female. But for the first few weeks of our lives human embryos are neither. Instead we have a protrusion called a tubercle. If you’re genetically male the Y chromosome instructs the gonads to become testicles. They also send testosterone to the tubercle, where it is converted into a potent hormone called dihydro-testosterone This transforms the tubercle into a penis. If you’re female and don’t make dihydro-testosterone then your tubercle becomes a clitoris.

When Dr Imperato investigated the Guavadoces she discovered the reason they don’t have male genitalia at birth is because they are deficient in an enzyme called 5-α-reductase, which normally converts testosterone into dihydro-testosterone. So they appear female when they are born, but around puberty, when they get another surge of testosterone, they sprout muscles, testes and a penis.

Apart from being slightly undersized everything works and the Guavadoces normally live out their lives as men, albeit with wispy beards and small prostates.

By a quirk of chance Dr Imperato’s research was picked up by the American pharmaceutical giant, Merck. They used her discovery to create a drug called finasteride, which blocks the action of 5-α-reductase. IT is now widely used to treat benign enlargement of the prostate and male pattern baldness. For which, I’m sure, many men are truly grateful

Since he’s become male Johnny has had a number of short term girlfriends, but he is still looking for the love of his life. “I’d like to get married and have children, a partner who will stand by me through good and bad”, he sighs wistfully.


“Countdown to Life – the extraordinary making of you” on Monday 21st September, BBC2, 9pm.



Video - https://youtu.be/6v_lXw7zYrI


Thanks to: http://nexusilluminati.blogspot.com



  

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