Latest topics
» Attorney General Jeff Sessions Delivers Remarks at The Heritage Foundation President's Club Meeting
Yesterday at 8:00 pm by Serena1

» The United States has been Hijacked w/ Judge Anna Von Reitz
Yesterday at 6:57 pm by PurpleSkyz

» Human 2.0 Is Almost Here: The Transhumanism Agenda Just Went Mainstream
Yesterday at 4:33 pm by PurpleSkyz

» April LaJune Client Comes Forward w/ Criminal Penalty PROOF!
Yesterday at 4:16 pm by topspin2

» Shocking New Evidence In Scalia Death Part One
Yesterday at 3:13 pm by PurpleSkyz

» Carrying Stones & Digging Holes Radio Show October 13, 2018
Yesterday at 1:50 pm by Consciousness Of Economic

» Fall/ Winter prep for Garden PT 1 & 2
Yesterday at 1:49 pm by Consciousness Of Economic

» SCAMMER ALERT! - Judy aka Quartz Crystal the Source Player is PLAYING You for DONATIONS!
Yesterday at 11:19 am by PurpleSkyz

» Ancient huge triangular formation found in the Nevada Desert
Yesterday at 10:05 am by PurpleSkyz

» Cherokee Nation Slams Warren for ‘Dishonoring Legitimate Tribal Citizens’ - 99.9% White
Yesterday at 9:02 am by PurpleSkyz

» RH Negative Blood? Alien? Nephilim? Human?
Yesterday at 8:54 am by PurpleSkyz

» Hurricane Cost Skyrockets - 29 Stealth Fighter Jets Unaccounted For
Yesterday at 7:52 am by PurpleSkyz

» Area 122: This secret laboratory in Antarctica hides something very strange
Yesterday at 7:49 am by PurpleSkyz

» He luckily got it on video or no one would have believed him - "Unknown"
Yesterday at 7:47 am by PurpleSkyz

» Giants of the Ancient World
Yesterday at 7:45 am by PurpleSkyz

» Mysterious Megaliths Of Ancient Mexico
Yesterday at 7:40 am by PurpleSkyz

» Argentina: Strange Ground Effects Caused by UFOs?
Yesterday at 7:35 am by PurpleSkyz

» THOSE PESKY ALCHEMICAL ROOSHIANS ARE AT IT AGAIN!
Yesterday at 7:26 am by PurpleSkyz

» RIP Bob Dean
Yesterday at 7:07 am by PurpleSkyz

» UFO News ~ Daytime UFO over Surrey, Canada plus MORE
Yesterday at 6:59 am by PurpleSkyz

» NIBIRU News ~ WHAT IS THIS NASA? WHICH PLANET? plus MORE
Yesterday at 6:51 am by PurpleSkyz

» Fluoride During Pregnancy Associated With ADHD in Children
Yesterday at 6:44 am by PurpleSkyz

» Kp Message 10-15-18… “Remaining ‘on Top’ within the Polarities”
Yesterday at 6:35 am by PurpleSkyz

» Earth Size UFO Returns To Sun Today, NASA/SOHO link
Yesterday at 6:23 am by PurpleSkyz

» UN Peacekeepers Caught Running Massive Child Sex Ring — Not One Person Jailed
Yesterday at 6:15 am by PurpleSkyz

» THE CORRUPT BUSINESS OF CHILD PROTECTIVE SERVICE …
Yesterday at 4:02 am by Serena1

» Los Alamos Star Gate/What was Really Happening?
Mon Oct 15, 2018 11:06 pm by PurpleSkyz

» "Cosmic Traffic Jam" / ALL of the planets rendezvous once again!
Mon Oct 15, 2018 10:37 pm by PurpleSkyz

» Vaccine doc slips up and tells the truth
Mon Oct 15, 2018 10:35 pm by PurpleSkyz

CLICK THE SUBSCRIBE BUTTON BELOW TO RECEIVE OUR DAILY NEWSLETTER

A 2ND EMAIL COMPLETES THE ACTIVATION PROCESS




CLICK THE PURPLE BUTTON TO VIEW OUR LATEST POSTS



ONLY NATURES MAGIC
No automatic alt text available.
ONLY NATURES MAGIC
Featuring Homemade Herbal Salves Made in the Ozarks
https://onlynaturesmagic.com



CONTACT PURPLESKYZ
FOR DETAILS


Oily Rocks Essentials
Oily Rocks
Boutique Essential Oil
Roller Bottles
https://oily-rocks.com



CONTACT PURPLESKYZ
FOR DETAILS


Key Word Topics:
11:11, Aliens, Angels, Antarctica, Ascension, Assange, Astral Projection, Auras, Bankers, Bitcoin, Blood Type, Booms, BRICS, Cabal, Cannabis, CBD, CERN, Chemtrails, CME's, Consciousness, Conspiracy Theories, Crypto Currency, Crystals, Dinar, Dinar Scam, Disclosure, Earthquakes, EMF, Empaths, Environment, ESP, ET's, False Flags, Federal Reserve, Flooding, Fluoride, Fracking, Fraud, Fukushima,GMO's, Herbs, History, Holistic, Illuminati, IMF, ISS, Ley Lines, Lucid Dreaming, Mandela Effect, Medical, Meteor, MKUltra, Monsanto, Morgellons, NASA, Nature, Nesara, Nibiru, Night Sky, NDE's, Numerology, NWO, OD's, Organic, Paranormal, Pizzagate, Planet X, Predictive Programming, Protests, Psychic, Q Anon, Radiation, Reincarnation, Remote Viewing, RH Negative Blood, RV, Sacred Geometry, Scams, Science, SETI, Shadow People, Shift, Sink Holes, Smart Meters, Space Force, Space X, Spirit Animals, Sun Simulator, Synchronicity, Technology, TDA, THC, UFO, Vatican, Vaccines, Volcano, WIFI, Wikileaks

You are not connected. Please login or register

Out Of Mind » THE INSANITY OF REALITY » SCIENCE » Researchers Find New DNA Structure in Living Human Cells

Researchers Find New DNA Structure in Living Human Cells

Go down  Message [Page 1 of 1]

PurpleSkyz

avatar
Admin
Researchers Find New DNA Structure in Living Human Cells


By
zIKY
-
April 29, 2018



A twisted ‘knot’ of DNA, the i-motif has never before been directly seen inside living cells. Image credit: Zeraati et al, doi: 10.1038/s41557-018-0046-3.
A team of scientists from the Garvan Institute of Medical Research and the Universities of New South Wales and Sydney has identified a new DNA structure — called the intercalated motif (i-motif) — inside living human cells.
Deep inside the cells in our body lies our DNA. The information in the DNA code — all 6 billion A, C, G and T letters — provides precise instructions for how our bodies are built, and how they work.
The iconic ‘double helix’ shape of DNA has captured the public imagination since 1953, when James Watson and Francis Crick famously uncovered the structure of DNA.
However, it’s now known that short stretches of DNA can exist in other shapes, in the laboratory at least — and scientists suspect that these different shapes might play an important role in how and when the DNA code is ‘read.’
“When most of us think of DNA, we think of the double helix. This research reminds us that totally different DNA structures exist — and could well be important for our cells,” said co-lead author Dr. Daniel Christ, from the Kinghorn Centre for Clinical Genomics at the Garvan Institute of Medical Research and St Vincent’s Clinical School at the University of New South Wales.
“The i-motif is a four-stranded ‘knot’ of DNA,” added co-lead author Dr. Marcel Dinger, also from the Garvan Institute of Medical Research and the University of New South Wales.
“In the knot structure, C letters on the same strand of DNA bind to each other — so this is very different from a double helix, where ‘letters’ on opposite strands recognize each other, and where Cs bind to Gs [guanines].”
Although researchers have seen the i-motif before and have studied it in detail, it has only been witnessed in vitro — that is, under artificial conditions in the laboratory, and not inside cells. In fact, they have debated whether i-motif DNA structures would exist at all inside living things — a question that is resolved by the new findings.
To detect the i-motifs inside cells, Dr. Christ, Dr. Dinger and their colleagues developed a precise new tool — a fragment of an antibody molecule — that could specifically recognize and attach to i-motifs with a very high affinity.
Until now, the lack of an antibody that is specific for i-motifs has severely hampered the understanding of their role.
Crucially, the antibody fragment didn’t detect DNA in helical form, nor did it recognize ‘G-quadruplex structures’ (a structurally similar four-stranded DNA arrangement).
With the new tool, the team uncovered the location of ‘i-motifs’ in a range of human cell lines.
Using fluorescence techniques to pinpoint where the i-motifs were located, the study authors identified numerous spots of green within the nucleus, which indicate the position of i-motifs.
The scientists showed that i-motifs mostly form at a particular point in the cell’s ‘life cycle’ — the late G1 phase, when DNA is being actively ‘read.’
They also showed that i-motifs appear in some promoter regions — areas of DNA that control whether genes are switched on or off — and in telomeres, ‘end sections’ of chromosomes that are important in the aging process.
“We think the coming and going of the i-motifs is a clue to what they do. It seems likely that they are there to help switch genes on or off, and to affect whether a gene is actively read or not,” said study first author Dr. Mahdi Zeraati, also from the Garvan Institute of Medical Research and the University of New South Wales.
“We also think the transient nature of the i-motifs explains why they have been so very difficult to track down in cells until now,” Dr. Christ added.
“It’s exciting to uncover a whole new form of DNA in cells — and these findings will set the stage for a whole new push to understand what this new DNA shape is really for, and whether it will impact on health and disease,” Dr. Dinger said.
The team’s results appear in the journal Nature Chemistry.
_____
Mahdi Zeraati et al. I-motif DNA structures are formed in the nuclei of human cells. Nature Chemistry, published online April 23, 2018; doi: 10.1038/s41557-018-0046-3
 
Source: http://www.sci-news.com
Wake The Sheeple!

Thanks to zIKY at: http://awakeandaware.ca



  

Back to top  Message [Page 1 of 1]

Permissions in this forum:
You cannot reply to topics in this forum