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OUT OF MIND » DISCLOSURE » RH NEGATIVE BLOOD TYPE ~ ORIGINS UNKNOWN » Why is ABO incompatibility not as severe as Rh incompatibility in pregnancy?

Why is ABO incompatibility not as severe as Rh incompatibility in pregnancy?

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PurpleSkyz

PurpleSkyz
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Why is ABO incompatibility not as severe as Rh incompatibility in pregnancy?



 rhesusnegatives@gmail.com April 6, 20170


The antibodies involved in ABO incompatibility are mainly of IgM variety and they are HUGE in mass and size, so they’re rarely able to traverse the placental barrier (if at all). On the other hand, antibodies involved in Rh incompatibility are mainly of the IgG variety which can easily traverse the placental barrier. Hence the latter is more serious.

Thanks to: http://www.rhesusnegative.net



  

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