- Rh Negative Facts
November 10, 20200
I have previously promised to look more into the potential association between non-secretor status and COVID-19. Here is a new study:
Association of ABO blood group and secretor phenotype with severe COVID‐19
I will highlight the part I consider quite interesting for now:
Although there was no significant association with the risk of thrombotic events (stroke, myocardial infarction, and venous thromboembolism), remarkably the nonsecretor phenotype was associated with lower in‐hospital mortality (adjusted OR, 0.53; 95% CI, 0.32‐0.83; P = .014). Mortality data according to O vs non‐O blood group and rs601338 variant are shown in Figure 1. Therefore, secretion of A/B antigens may promote COVID‐19 progression, but further studies will be necessary to confirm the protective effect of nonsecretor phenotype.
Thanks to Mike at: https://www.rhesusnegative.net