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U.S. Health Officials Accuse AstraZeneca of Misrepresenting Efficacy Data

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PurpleSkyz

PurpleSkyz
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U.S. Health Officials Accuse AstraZeneca of Misrepresenting Efficacy Data


Posted on March 24, 2021


U.S. Health Officials Accuse AstraZeneca of Misrepresenting Efficacy Data AstraZenenca-incomplete-view-trial-data-feature-1-800x417

By Megan Redshaw
An independent trial review board says AstraZeenca may have included outdated information about its clinical trial results in a press release.
In a “highly unusual” statement Tuesday, a U.S. health agency said AstraZeneca may have included “outdated information” in its clinical trial results, which may have led to the vaccine maker providing the public with an incomplete view of its efficacy data.
The statement by the National Institute of Allergy and Infectious Diseases (NIAID) came less than a day after the pharmaceutical company said its vaccine was 79% effective against COVID and 100% effective against severe or critical disease and hospitalization.
“We urge the company to work with the Data and Safety Monitoring Board (DSMB) to review the efficacy data and ensure the most accurate, up-to-date efficacy data be made public as quickly as possible,” the NIAID said.
AstraZeneca immediately responded saying the numbers published Monday were based on a “pre-specified interim analysis with a data cut-off” of Feb. 17. The company promised to “immediately engage with the DSMB to share their primary analysis with the most up-to-date efficacy data” and to issue the results of the primary analysis within 48 hours.
The DSMB is an independent expert group that sees trial data before the pharmaceutical companies, the doctors running the trials or even the U.S. Food and Drug Administration (FDA), according to CNN. It has the authority to advise a company of positive interim findings or to halt a trial over safety concerns, which is what happened to AstraZeneca last September after a study participant developed neurological symptoms.

https://stuartbramhall.wordpress.com/2021/03/24/u-s-health-officials-accuse-astrazeneca-of-misrepresenting-efficacy-data/

Thanks to: https://stuartbramhall.wordpress.com



  

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