OUT OF MIND
Would you like to react to this message? Create an account in a few clicks or log in to continue.
Latest topics
» Here’s the Proof that Ivermectin Cures Covid and How to Get It
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:53 am by PurpleSkyz

» Nullifying Nuremberg
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:45 am by PurpleSkyz

» What Would a Complete Supply Chain Breakdown Really Look Like?
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:29 am by PurpleSkyz

» Covid-19 deaths are rising and official data shows 87% of the people who have died were VACCINATED
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:22 am by PurpleSkyz

» Remington Offers $33 Million Settlement to Families of Sandy Hook Shooting Victims
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:17 am by PurpleSkyz

» Benjamin bla bla blah Fulford - 8/02/2021 - Getting To Know The North Koreans
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:11 am by PurpleSkyz

» Covid vaccines make the virus MORE dangerous for the vaccinated, especially Pfizer’s viral vector jab
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 9:03 am by PurpleSkyz

» Portugal’s Children Are ‘Suddenly Becoming Ill All At Once’
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 8:58 am by PurpleSkyz

» Sweden: Despite Variants, No Lockdowns, No Daily Covid Deaths
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 8:54 am by PurpleSkyz

» CDC/VAERS Stats thru 7/23/21
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 8:48 am by PurpleSkyz

» Clif High - Tidal Woo
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 8:38 am by PurpleSkyz

» Local government in Philippines declares that unvaccinated people are barred from purchasing FOOD
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 12:18 am by PurpleSkyz

» Australians Who Post Independent Media Content Online Could Face $11,000 Fines
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyToday at 12:07 am by PurpleSkyz

» Crop Circles 2021 - Spiers Lane, Nr Swarraton, Hampshire. Reported 1st August.
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 8:03 pm by PurpleSkyz

» Stunning Perseid fireball over Toledo
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 7:21 pm by PurpleSkyz

» The Consistent Inconsistencies Of The Vaccination Discussion
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 9:13 am by PurpleSkyz

» CIA Document Reveals Astronauts Conducted Telepathy Experiments in Space
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 9:06 am by PurpleSkyz

» The MH 17 False Flag…One of Many
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 9:02 am by PurpleSkyz

» Must Watch! Thousands March in France as Nationwide Opposition to Covid ID Shows No Signs of Fizzling Out
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 8:51 am by PurpleSkyz

» Gov DeSantis BANS Florida Schools From Forcing Children to Wear Masks
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 8:47 am by PurpleSkyz

» Tsunami sirens sound in Alaska after 7th largest earthquake in US history hits off coast
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 8:36 am by PurpleSkyz

» Bad-clown Rising - Tokyo Olympics plus MORE
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia EmptyYesterday at 8:17 am by PurpleSkyz

You are not connected. Please login or register

OUT OF MIND » BREAKING NEWS & HOT TOPICS » COVID-19 » Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia

Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia

Go down  Message [Page 1 of 1]

PurpleSkyz

PurpleSkyz
Admin
Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia 3d0aae6a96a95197

Cleveland Clinic-Led Study Shows Covid-19 Leads to Brain Changes & Alzheimer’s-Like Dementia
June 14, 2021


A new Cleveland Clinic-led study has identified mechanisms by which COVID-19 can lead to Alzheimer’s disease-like dementia. The findings, published in Alzheimer’s Research & Therapy, indicate an overlap between COVID-19 and brain changes common in Alzheimer’s, and may help inform risk management and therapeutic strategies for COVID-19-associated cognitive impairment.
Reports of neurological complications in COVID-19 patients and “long-hauler” patients whose symptoms persist after the infection clears are becoming more common, suggesting that SARS-CoV-2 (the virus that causes COVID-19) may have lasting effects on brain function. However, it is not yet well understood how the virus leads to neurological issues.
Feixiong Cheng, Ph.D., assistant staff in Cleveland Clinic’s Genomic Medicine Institute and lead author on the study says:
“While some studies suggest that SARS-CoV-2 infects brain cells directly, others found no evidence of the virus in the brain. Identifying how COVID-19 and neurological problems are linked will be critical for developing effective preventive and therapeutic strategies to address the surge in neurocognitive impairments that we expect to see in the near future.”
In the study, the researchers harnessed artificial intelligence using existing datasets of patients with Alzheimer’s and COVID-19. They measured the proximity between SARS-CoV-2 host genes/proteins and those associated with several neurological diseases where closer proximity suggests related or shared disease pathways. The researchers also analyzed the genetic factors that enabled SARS-COV-2 to infect brain tissues and cells.
While researchers found little evidence that the virus targets the brain directly, they discovered close network relationships between the virus and genes/proteins associated with several neurological diseases, most notably Alzheimer’s, pointing to pathways by which COVID-19 could lead to Alzheimer’s disease-like dementia. To explore this further, they investigated potential associations between COVID-19 and neuroinflammation and brain microvascular injury, which are both hallmarks of Alzheimer’s. Dr. Cheng explained:
“We discovered that SARS-CoV-2 infection significantly altered Alzheimer’s markers implicated in brain inflammation and that certain viral entry factors are highly expressed in cells in the blood-brain barrier. These findings indicate that the virus may impact several genes or pathways involved in neuroinflammation and brain microvascular injury, which could lead to Alzehimer’s disease-like cognitive impairment.
“Ultimately, we hope to have paved the way for research that leads to testable and measurable biomarkers that can identify patients at the highest risk for neurological complications with COVID-19.”
The researchers also found that individuals with the allele APOE E4/E4, the greatest genetic risk factor for Alzheimer’s, had decreased expression of antiviral defense genes, which could make these patients more susceptible to COVID-19.
Dr. Cheng and his team are now working to identify actionable biomarkers and new therapeutic targets for COVID-19-associated neurological issues in COVID long-haulers using cutting-edge network medicine and artificial intelligence technologies.
Yadi Zhou, Ph.D.; Jielin Xu, Ph.D., and Yuan Hou, Ph.D., are co-first authors on the study. The study was supported by the National Institute on Aging, the National Heart, Lung, and Blood Institute, the National Institute of Neurological Disorders and Stroke, and Cleveland Clinic’s VeloSano Pilot Program.
Cleveland Clinic

Headline Image: Feixiong Cheng, Ph.D. via Cleveland Clinic

https://bendedreality.com/cleveland-clinic-led-study-shows-covid-19-leads-to-brain-changes-alzheimers-like-dementia/


Thanks to: https://bendedreality.com



  

Back to top  Message [Page 1 of 1]

Permissions in this forum:
You cannot reply to topics in this forum