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Recombinant Antigens for 2015-2023 Influenza Vaccine Strains
Seasonal flu is a common infectious disease of the respiratory tract caused by influenza virus. There are four types of influenza virus, influenza type A, B, C, and D. The A and B types are of most interest to the medical community because they are the culprits for seasonal epidemics. Occasionally, influenza A, like the A/California/04/09 (H1N1) and A/Hong Kong/1/1968 (H3N2), can even cause global pandemics.
Vaccination is the most effective way to prevent flu infection. Each year, several different flu strains are selected as vaccine candidates based on surveillance data of the recent isolates and the performance of the vaccines from the previous season. In recent decades, most influenza vaccines are trivalent or quadrivalent, composed of one H1N1, one H3N2, and either one or two type B viruses (Yamagata and Victoria lineage).
Sino Biological offers recombinant flu antigen products under its ProVir
viral antigen collection. The product line covers Hemagglutinin (HA), Neuraminidase (NA), and Nucleoprotein (NP) proteins, from all WHO-recommended vaccine strains in recent years. These antigens can be used to analyze vaccine-induced antibody response. In addition, Sino Biological also develops a large collection of monoclonal antibodies against the flu antigens. These reagents can help facilitate relevant assay development.Year 2022-2023
A/Victoria/2570/2019 (H1N1) Recommended for Egg-based (quadrivalent,trivalent) Vaccine HA: 40787-V08H, 40787-V08H1 NA: 40785-V08B NP: 40774-V08B A/Wisconsin/588/2019 (H1N1) Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40787-V08H, 40787-V08H1 NA: 40785-V08B NP: 40774-V08B B/Phuket/3073/2013 Recommended for Egg-based, Cell- or recombinant-based (quadrivalent) Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B A/Darwin/9/2021 (H3N2) Recommended for Egg-based (quadrivalent, trivalent) Vaccine HA: 40859-V08H (pre-order), 40859-V08B (pre-order) NA: 40860-V08B (pre-order) NP: 40858-V08B (pre-order) B/Austria/1359417/2021 (B/Victoria lineage) Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40862-V08H (pre-order), 40862-V08B (pre-order) NA: 40863-V08B (pre-order) NP: 40861-V08B (pre-order) A/Darwin/6/2021 (H3N2) Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40868-V08H (pre-order), 40868-V08B (pre-order) NA: 40869-V08B (pre-order) NP: 40858-V08B (pre-order)
Year 2021-2022
A/Victoria/2570/2019 (H1N1) Recommended for Egg-based (quadrivalent,trivalent) Vaccine HA: 40787-V08H, 40787-V08H1 NA: 40785-V08B NP: 40774-V08B A/Wisconsin/588/2019 (H1N1) Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40787-V08H, 40787-V08H1 NA: 40785-V08B NP: 40774-V08B B/Washington/02/2019 Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40722-V08H NA: 40790-V08B NP: 40755-V08B B/Phuket/3073/2013 Recommended for Egg-based, Cell- or recombinant-based (quadrivalent) Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B A/Cambodia/E0826360/2020 (H3N2) Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40789-V08H, 40789-V08H1 NA: 40784-V08B NP: 40778-V08B
Year 2020-2021
A/Guangdong-Maonan/SWL1536/2019 (H1N1) Recommended for Egg-based (quadrivalent, trivalent) Vaccine HA: 40717-V08H NP: 40723-V08B A/Hong Kong/2671/2019 (H3N2) Recommended for Egg-based (quadrivalent, trivalent) Vaccine HA: 40721-V08H NP: 40753-V08B A/Hawaii/70/2019 (H1N1) Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40717-V08H NP: 40724-V08B A/Hong Kong/45/2019 (H3N2) Recommended for Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40765-V08H NP: 40754-V08B B/Phuket/3073/2013 Recommended for Egg-based, Cell- or recombinant-based (quadrivalent) Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B B/Washington/02/2019 Recommended for Egg-based, Cell- or recombinant-based (quadrivalent, trivalent) Vaccine HA: 40722-V08H NA: 40790-V08B NP: 40755-V08B
Year 2019-202
A/Brisbane/02/2018 (H1N1) Recommended for Egg-based (quadrivalent) Vaccine HA: 40719-V08H NA: 40767-V08B NP: 40776-V08B A/Kansas/14/2017 (H3N2) Recommended for Egg-based (quadrivalent) Vaccine HA: 40720-V08H NA: 40766-V08B NP: 40779-V08B B/Phuket/3073/2013 Recommended for Egg-based (quadrivalent) Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B B/Colorado/06/2017 Recommended for Egg-based (quadrivalent); trivalent Vaccine HA: 40581-V08H NP: 40782-V08B
Year 2018-2019
A/Michigan/45/2015 (H1N1) Recommended for quadrivalent Vaccine HA: 40567-V08H1 NA: 40568-V08B NP: 40777-V08B A/Singapore/INFIMH-16-0019/2016 (H3N2) Recommended for quadrivalent Vaccine HA: 40580-V08H NP: 40779-V08B B/Phuket/3073/2013 Recommended for quadrivalent Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B B/Colorado/06/2017 Recommended for quadrivalent; trivalent Vaccine HA: 40581-V08H NP: 40782-V08B
Year 2017-2018
A/Michigan/45/2015 (H1N1) Recommended for trivalent Vaccine HA: 40567-V08H1 NA: 40568-V08B NP: 40777-V08B A/Hong Kong/4801/2014 (H3N2) Recommended for trivalent Vaccine HA: 40555-V08B NA: 40569-V08B NP: 40781-V08B B/Brisbane/60/2008 Recommended for trivalent Vaccine HA: 40016-V08B NA: 40203-VNAHC NP: 40783-V08B B/Phuket/3073/2013 Recommended for quadrivalent Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B
Year 2016-2017
A/California/7/2009 (H1N1) Recommended for trivalent Vaccine HA: 11085-V08B NP: 40205-V08B A/Hong Kong/4801/2014 (H3N2) Recommended for trivalent Vaccine HA: 40555-V08B NA: 40569-V08B NP: 40781-V08B B/Brisbane/60/2008 Recommended for trivalent Vaccine HA: 40016-V08B NA: 40203-VNAHC NP: 40783-V08B B/Phuket/3073/2013 Recommended for quadrivalent Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B
Year 2015-2016
A/California/7/2009 (H1N1) Recommended for trivalent Vaccine HA: 11085-V08B NP: 40205-V08B A/Switzerland/9715293/2013 (H3N2) Recommended for trivalent Vaccine HA: 40497-V08B NA: 40499-V08B B/Brisbane/60/2008 Recommended for quadrivalent Vaccine HA: 40016-V08B NA: 40203-VNAHC NP: 40783-V08B B/Phuket/3073/2013 Recommended for trivalent Vaccine HA: 40498-V08B NA: 40502-V07B NP: 40500-V08B
https://www.sinobiological.com/research/virus/influenza-vaccine-strains-2015-2021?utm_source=livescience&utm_medium=newsletter&utm_campaign=apr-influenza-vaccine
Thanks to: https://www.sinobiological.com
