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OUT OF MIND » HEALTH & MEDICAL INFO » RH NEGATIVE BLOOD » Bombay Blood Group: The Real Universal Donor

Bombay Blood Group: The Real Universal Donor

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PurpleSkyz

PurpleSkyz
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Bombay Blood Group: The Real Universal Donor



  • Rh Negative Facts

 Mike Dammann
February 23, 20200



Bombay Blood Group: The Real Universal Donor 1176px-Bombay.svg_
Technically speaking, O negative blood is not the universal donor. A regular O negative cannot donate to a Bombay blood group O(h) lacking the H antigen regular blood type O people have.



Hh or the Bombay blood group, is a rare blood type. This blood phenotype was first discovered in Bombay, now known as Mumbai, in India, by Dr. Y. M. Bhende in 1952. It is mostly found in South Asia (India, Bangladesh, Pakistan) and parts of Middle East such as Iran.
Bombay Blood Group: The Real Universal Donor 37775480_2108598322688990_2449726810221445120_nOn the island of Reunion, the frequency of Bombay blood is unusually high as well.
Individuals with the rare Bombay phenotype (hh) do not express H antigen (also called substance H), the antigen which is present in blood group O. As a result, they cannot make A antigen (also called substance A) or B antigen (substance B) on their red blood cells, whatever alleles they may have of the A and B blood-group genes, because A antigen and B antigen are made from H antigen. For this reason people who have Bombay phenotype can donate red blood cells to any member of the ABO blood group system (unless some other blood factor gene, such as Rh, is incompatible), but they cannot receive blood from any member of the ABO blood group system (which always contains one or more of A, B or H antigens), but only from other people who have Bombay phenotype.
This very rare phenotype is generally present in about 0.0004% (about 4 per million) of the human population, though in some places such as Mumbai (formerly Bombay) locals can have occurrences in as much as 0.01% (1 in 10,000) of inhabitants. Given that this condition is very rare, any person with this blood group who needs an urgent blood transfusion will probably be unable to get it, as no blood bank would have any in stock. Those anticipating the need for blood transfusion may bank blood for their own use, but of course this option is not available in cases of accidental injury.
https://www.ncbi.nlm.nih.gov/books/NBK2268/

https://www.rhesusnegative.net/staynegative/bombay-blood-group-the-real-universal-donor/

Thanks to: https://www.rhesusnegative.net



  

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